CVE-2026-31970: HTSlib is a library for reading and writing bioinformatics file formats.

HTSlib is a library for reading and writing bioinformatics file formats.

HTSlib is a library for reading and writing bioinformatics file formats. GZI files are used to index block-compressed GZIP [BGZF] files. In the GZI loading function, `bgzf_index_load_hfile()`, it was possible to trigger an integer overflow, leading to an under- or zero-sized buffer being allocated to store the index. Sixteen zero bytes would then be written to this buffer, and, depending on the result of the overflow the rest of the file may also be loaded into the buffer as well. If the function did attempt to load the data, it would eventually fail due to not reading the expected number of records, and then try to free the overflowed heap buffer. Exploiting this bug causes a heap buffer overflow. If a user opens a file crafted to exploit this issue, it could lead to the program crashing, or overwriting of data and heap structures in ways not expected by the program. It may be possible to use this to obtain arbitrary code execution. Versions 1.23.1, 1.22.2 and 1.21.1 include fixes for this issue. The easiest work-around is to discard any `.gzi` index files from untrusted sources, and use the `bgzip -r` option to recreate them.

Description from the National Vulnerability Database, published by GitHub

What it means for a small business

If your business uses htslib, install the vendor's update. If you're not sure whether you use it, ask whoever manages your computers.

How likely is an attack? The Exploit Prediction Scoring System, run by FIRST (the global association of security response teams), puts the odds of this one being exploited in the next 30 days at 0.47%, higher than 40% of CVEs. That’s low, but low isn’t zero, and the odds jump the day someone publishes an exploit. Scored October 28, 2026, updated daily.

Check your own setup

Website check: reads what your site runs from the outside (WordPress version, plugins it can see, old server software) and matches it against this database.
Server check: what your web server says about itself, and whether that version has known flaws.

Sources

Part of the Huttenlocher Technologies vulnerability database, refreshed twice a day from CISA and the NVD. The title, category and plain-language guidance are ours; check the linked record before acting on a detail. This is general guidance, not a review of your systems.

Weekly security brief

The flaws that hit local websites, every Friday.

One short email: what got exploited this week, which WordPress plugins broke, and what to check. Unsubscribe in one click.